Applicable Products
| 2041 | 2'-OMe-Bz-A-CE Phosphoramidite |
| 2042 | 2'-OMe-Bz-C-CE Phosphoramidite |
| 2043 | 2'-OMe-Ac-C-CE Phosphoramidite |
| 2044 | 2'-OMe-dmf-G-CE Phosphoramidite |
| 2045 | 2'-OMe-U-CE Phosphoramidite |
| 2083 | 2'-OMe-Pac-A-CE Phosphoramidite |
| 2084 | 2'-OMe-iPr-Pac-G-CE Phosphoramidite |
| 2310 | 2'-OMe-U-SynBase™ CPG 1000/110 |
| 2311 | 2'-OMe-dmf-G-SynBase™ CPG 1000/110 |
| 2312 | 2'-OMe-Bz-A-SynBase™ CPG 1000/110 |
| 2313 | 2'-OMe-Bz-C-SynBase™ CPG 1000/110 |
| 2314 | 2'-OMe-Ac-C-SynBase™ CPG 1000/110 |
Physical & Dilution Data
Dilution volumes (in ml) are for 0.1M solutions in dry acetonitrile (4050). Adjust accordingly for other concentrations. For µmol pack sizes, products should be diluted as 100µmol/ml to achieve 0.1M, regardless of molecular weight.
Item |
Mol. Formula |
Mol. Wt. |
Unit Wt. |
250mg |
500mg |
1g |
| 2041 | C48H54N7O8P | 887.97 | 343.24 | 2.82 | 5.63 | 11.26 |
| 2042 | C47H54N5O9P | 863.95 | 319.21 | 2.89 | 5.79 | 11.57 |
| 2043 | C42H52N5O9P | 801.88 | 319.21 | 3.12 | 6.24 | 12.47 |
| 2044 | C44H56N8O8P | 855.95 | 359.24 | 2.92 | 5.84 | 11.68 |
| 2045 | C40H49N4O9P | 760.82 | 320.20 | 3.29 | 6.57 | 13.14 |
| 2083 | C49H56N7O9P | 917.99 | 343.24 | 2.72 | 5.45 | 10.89 |
| 2084 | C52H62N7O10P | 976.07 | 359.24 | 2.56 | 5.12 | 10.25 |
| 2310 | - | - | 320.20 | - | - | - |
| 2311 | - | - | 359.24 | - | - | - |
| 2312 | - | - | 343.24 | - | - | - |
| 2313 | - | - | 319.21 | - | - | - |
| 2314 | - | - | 319.21 | - | - | - |
Coupling
To optimise efficiency a 6min coupling time is recommended for the phosphoramidites. Use of the supports does not require any change to the synthesis cycle.
Cleavage & Deprotection
Standard oligonucleotide deprotection conditions can be applied when deprotecting an oligo synthesised using these products.
Ac-C (2043) must be used when employing AMA deprotection (10min at 65°C). UltraMILD deprotection can be used with Pac-A (2083), iPr-Pac-G (2084) and 2043. Bz-C (2042 or 2313) cannot be used with AMA deprotections.
Storage & Stability
All products are stored refrigerated at 2 to 8˚C. Stability in solution is 3-5 days.
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