Applicable Products
| 2326 | 3'-Glyceryl SynBase CPG 1000 |
Physical Data
Item |
Mol. Formula |
Mol. Wt. |
Unit Wt. |
| 2236 | - | - | 154.06 |
Coupling
As with all non-nucleosidic supports, an additional deblock step is required.
Cleavage & Deprotection
This is dependent on the nucleobase protection and other modifications but is typically ammonium hydroxide at 55ºC for 4h, or AMA at 65ºC for 10min.
Storage & Stability
Store dry in a freezer at –10 to –30°C.
References
- For oxidation and reduction methods for converting the glycerol group, see: Convenient synthesis of oligonucleotides with a 3’-phosphoglycolate and 3’-phosphoglycaldehyde terminus, H. Urata and M. Akagi, Tetrahedron Lett., 34, 4015-4018 (1993). [Abtract]
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